What is the connection between proteins and your DNA – and why did Donna Gates bring NanoVi® into her summit on genetics and epigenetics?
Donna Gates has been interested in health and vitality since she was seven years old. While most of us were playing hopscotch (yes this was many years ago) she was already interested in ways to avoid the deterioration she saw in an elderly relative. It is no surprise that Donna went on to make huge contributions to our understanding of health and wellbeing – and thus to anti-aging. And Donna is living proof that her suggestions work.
In this video, Donna Gates interviews Rowena Gates on the role of the NanoVi device in genetics and epigenetics. They discuss the process of going from the DNA blueprint to the functioning protein. Enjoy!
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Transcript for Genius of Your Genes Summit Video on NanoVi® Technology
Donna Gates Interview with Rowena Gates
Donna Gates:
Welcome to the Genius of your Genes Summit.
Now, I know a lot of people listening are practitioners, and they probably know something about their genes, about DNA. I think a lot of people who know the word DNA. We know it is our genes, but for many, many people listening, they do not know much more beyond that. But DNA is of course where our genes are, and most of us have; well, all of us actually, have the same DNA, but some of us have different mutations or SNPs or variants. And that is actually what makes us unique, but that is really just a very, very small amount of our DNA, most of our DNAs are all alike.
Now, DNA is really interesting, because it has the ability to repair itself. If we are constantly abusing our bodies, like many people are with the wrong diet, even if they are eating the right diet, but it is the wrong diet for them for their genes, they are not getting enough sleep, they are under constant stress, they do not exercise. You know the usual things that we all know are bad for us, you know, not getting enough water and so on, that is what begins to damage the DNA, and it has the ability to repair itself, but not if you are constantly weakening it. Now, what supports the DNA in being able to repair itself are all the good things. You know having a diet that is just right for you, a personalized diet, sleeping the right number of hours, seven and a half to eight hours, what works for you, and really taking care of yourself and slowing down the aging process and aging really well, exercising in the way that is best for you and your needs, reducing stress, getting enough sleep, that is what we have to do to support the DNA. So then it will repair itself on its own, because it is designed to do that.
Naturally though, as we age, the DNA does this not as well, we get older and older and our DNA does not have the ability to repair itself. I asked Rowena Gates, same last name as me, to please talk to us a little bit about DNA repair, because it is super important, and I have known Rowena really, really long time. She is going to be telling us about a piece of equipment called the NanoVi. I have had two versions, the first version, and now I have a more recent version of the NanoVi, and I did not understand years ago why it was good, I just saw amazing things, far better sleep, I would lend my NanoVi machine to other people, and they would have great results.
Not too long ago one of my daughters had a fall and had a really bad injury in her brain, and it was one of the most important things she did to help recover from that. Rowena helped her and guided her through that too, but so you know, this is just great, you may have heard of the NanoVi before, but you may not have, I want to be able to use it as an example of the DNA repairing itself. So, Rowena after that very long introduction, thank you for waiting patiently. Rowena is the one of the partners in a company called Eng3 Corporation, that is spelled Eng, the number 3 corporation. So, thanks for being here Rowena.
Rowena Gates:
It is a pleasure to be here. I am a fan and a friend, so I really appreciate it. So, we have a great interest in DNA repair, and it is a very complicated process, and there is many aspects of it, where the support offered by the device we have is helpful. You mentioned the primary DNA damage to the code, it is very fragile and sensitive, and there is always the potential for damage. The body does great work to try to prevent that damage or repair the damage as quickly as possible to the primary DNA code. But there are other places that things can go wrong, and these are especially interesting, because they are along the lines of epigenetics.
You have already mentioned those factors that influence your epigenetics. I like to think of it as a big machine, and the DNA is being transcribed by the RNA, which is then translated into the protein, and at any step along the way things can go wrong. If you think of this very complicated machine, where parts of it can influence other parts of it, and the product from the machine can actually come back and influence how the machine runs and how it is maintained, then you are getting an idea of this really complicated machinery that ends up with all the functions in our body.
One of the most interesting things is if the product could come back, instead of just being shipped out like a normal machine, it could come back and interfere with how the machine itself is operating. This could be good, because there is feedback and it tells your body to upregulate or do things differently to address different situations. On the other hand, if something goes wrong, that can be a loop that is very detrimental. That is where, as much as you can reduce the potential for damage, the less DNA damage you will have and really keep healthy and strong.
They have certainly shown that this is a big factor in aging. In studies of people that are over 100 years old, looking at what makes them special, it is really interesting that one of the things that shows up is a particular gene and the protein that it makes is one that repairs oxidative stress damage, which is all that cellular damage that we have ongoing, but also can increase or decrease depending on our lifestyle. So, there is very clearly an epigenetic component, where if you could reduce the risk of having the damage take place during this complicated process, then you are going to keep your genes healthier. And Donna as you said, that is really critical, that is the blueprint. So, the stronger the DNA, the more it remains pure and undamaged, then that is an important factor for longevity.
Donna Gates:
Well, you know it is also nice too for people that think, well I have lived a big chunk of my life here, and I really have not been taking care of myself, but I am now, can I repair the damage?
Rowena Gates:
It depends, and I am not the perfect expert for this that question probably, but I have a personal belief that the body just has this tremendous capacity for repair. So, I think that you really cannot overestimate what it is possible to repair, and we have seen incredible things, and sometimes it just needs some help, like a good diet, you know, the boost that can be provided to it and so I kind of see it as being unlimited, and I do not think science has shown me wrong.
Donna Gates:
Well, I think too, like for example, let us say someone really focuses on detoxification, and they get a lot of toxins out of their body, you know, get rid of heavy metals, for example. They nourish themselves well, and they are feeding their DNA and all their genes and all the cells well, yeah, I agree there is, who knows what the body is doing there in lots of ways and regenerating, because it is always regenerating new healthy cells. So, now it is able to start, I hear things like every seven years, we have got all new cells in our body. So, obviously as we go down the road and we are constantly producing new healthy cells, then that seems to make sense to me, but I also know that on the other side of that, if you are not taking care of yourself, and you are doing all the wrong things that I mentioned earlier, that the cell reproduces itself, it makes daughter cells, and if you are damaging that cell, basically the daughter cells are damaged as well. They are just not even healthy normal cells, basically. So, I think taking care of the cells, you do have is the focus and detoxification and eating well and everything that we should be doing.
Can you explain to us what the NanoVi machine is and how it works, and why it would be good for DNA repair?
Rowena Gates:
Absolutely. Sort of the last step in that machinery is that the protein is produced and there are probably close to a million different proteins in the body, we do not know what most of them are yet. Those proteins do all the work, they transport things, they act as messengers, they store, they create our skeleton, our structure, and just an endless supply. All the work that is getting done in the body is done by proteins. So, that is the end result of the DNA to RNA process. These proteins have to function correctly in order to keep the whole system healthy, and the proteins are also doing repair. It is interesting because they know of about 25 DNA repair proteins, only a few of them do they really understand exactly how they work. They include to say a tumor suppressant protein or one that addresses oxidative stress, which are really good things, but those proteins also have the potential to be what are called oncogenes, which are genes that can go into producing tumor cells.
Donna Gates:
One gene that pops to my mind is the BRCA gene, there is such a fear about that gene because it is gotten a lot of publicity as everybody knows but that is exactly how that gene works, it is a gene that turns off cancer, and so if you have got a variant there or a number of variants, there is a bunch of BRCA genes actually, but then that gene is not working, it is not turning off the cancer and then you are likely to get cancer.
Rowena Gates:
Exactly, and the really well-known one there is p53, it is a cancer suppressant gene, but if it goes wrong, which can be the epigenetic factors that make it go wrong, then it can be an oncogene and cause cancer. So, some of the ones that are most helpful and most critical also have this high potential to do things that are really not good if things get too far out of balance. The idea to keep it in balance, keep the damage in check and repair things on the fly is so important. I was saying that the last step of the proteins may be to circle back, those proteins go back and influence everything.
You could also have perfect expression of the proteins, everything is great, so you have gone through multiple processes to get from your DNA to the final stage, but at that stage, they have to fold. There are very complicated three-dimensional structures that the proteins form. So, if you do not have the correct folding, you can also have damage. An example of this is the body has this amazing wisdom so when it is challenged, it will upregulate the production of a protein. Then it might kind of over produce to the point that within the cell, the proteins cannot fold and go do their work fast enough to keep up with this production. If this happens, you have this unfolded protein, and if they accumulate, then that can add up badly for the cell. So, it is sort of complicated at every step and all these things have to keep going correctly and that is where our side of things comes in.
At that last stage of the protein folding is where we support that activity, so proteins can go off and work effectively. As you said the science of how that is done, which is done through the cellular water, but that science, I think we met before, most of that was even figured out. In terms of how the water is working and the nature of the water, and the idea that there is not just the solid, liquid, and gas, there is actually a fourth phase of water, which is very special. It is the water that is in the cells, and so that is actually the level that our technology operates on, and so the goal is to support all of those protein functions, some of which are going back to repair DNA or any other part of that machinery, either the transcription into RNA or the translation into the protein or, however, those are occurring. So, we do not actually follow that in any detail, we just provide a better environment.
Donna Gates:
Well, you know, so you have a picture or a sample of what the NanoVi machine looks like, and can you just kind of describe it, it is very pretty, and it got smaller overtime, and you know how is it even developed.
Rowena is back with the Eng machine right beside her. So, we do not have to guess what it looks like, but could you tell us how it was developed.
Rowena Gates:
Yeah, absolutely. It was developed by my partner, Hans Eng, he is the moving force behind it. He just worked through the science related to initiating repair in the body, areas of science that were known by cell biology actually and recognized – then mimicked – a specific signal or wavelength that the body naturally produces. So, he copied that, to produce it in the technology and then augment that cellular environment. It is really only augmenting what the body normally does and what the body does less well as we age, and then it is delivered through humidity, this is just a slightly humid airstream. You breathe in either from the tube or from the nasal tubes, and it is all about the humidity and the water, it is then contacting your cellular water and influencing your body through the water.
Donna Gates:
Well, one of the most amazing things that consistently happens for everybody that is very noticeable is how relaxed they become, and there is no question, they sleep well. When I first had my very first version, I literally I was so unhealthy, then I literally brought it into the bed and it would turn itself off, and when I would wake up, turn it back on, go back to sleep, and it really helped me sleep better. Which is really critical for recovery, and now fortunately, you know, you can keep it on for a long time.
Rowena Gates:
Oh yeah, this one, you can put it on continuous mode even, so it never shuts off, which is maybe a little too much.
Donna Gates:
How long would you advise people to use it at a time?
Rowena Gates:
There is three different models, and it depends on how powerful the device is. So, if it is the most powerful device, just a 15-minutes or half hour, maybe even a couple of times a day if a person has enough time for that. So, it is one of those things you cannot use it too much, because of the way it works, and most of us could use more than just sort of a basic level, because we are either getting on an age or we are performing at a really high level or some people are ill and then they can use more of it.
Donna Gates:
But it is not oxygen.
Rowena Gates:
It is not oxygen. It is interesting because your body will often respond as if there is added oxygen, but it is only because there is better utilization of it. So, it will help with the utilization of oxygen, and then you notice some characteristics of concentrated oxygen, like if a person is low in their blood oxygen levels and they go up. That is something we associate with concentrated oxygen; however, you could get the same result if you just utilize the oxygen better.
Donna Gates:
Well, are you breathing it in or is it actually doing something special to the lungs?
Rowena Gates:
It can be more noticeable in the lungs for certain people, and that is the first point of contact to all the fluid, there is a very big watery surface there. However, it does not only affect the contact, it effects throughout the system, because of the way the water is in the body. 99% of the molecules in the body are water, and they are all connected, so one influences the other very rapidly across the system. So, it does not have to be in contact with a specific area for it to benefit that area.
Donna Gates:
Well, do you have any understanding exactly how it affects the nervous system, so that it is so relaxing, and is there either research or stories from people about the effect on the brain?
Rowena Gates:
Yes, to both of those. One interesting thing about the body is when you give it a little extra help, it will always try to come back into balance. We can measure that that is the impact it has on the autonomic nervous system; it is to rebalance it. And that is easily measured with heart rate variability and the NanoVi will always show that improvement because it helps the body and then the body goes back, finds a better balance. You can see that with other measures too, like hormones or different areas where the body will rebalance with it.
Donna Gates:
Well, who are your customers, who purchases, I know Dave Asprey has one, but I do not mean famous people that everybody knows, I mean normal people, like I know you have a lot of doctors put it in their offices, but just people like what are people noticing I guess is what I am asking?
Rowena Gates:
Well, one thing you just mentioned was the brain and mental performance, which is an area I love, and we have had a lot of results, especially lately, high performance mental function, and that can be measured with brain scans, which people have done to show before and after, and again the brain will rebalance and you reduce inappropriate brain activity by using the device. So, that is exciting to see, and it is also a bigger focus, I see it as a really big growing area of concern for people, because they want to preserve their mental performance, and so that concentration, executive function, decision making fatigue, all those aspects of mental performance are reasons that people get a NanoVi device.
Donna Gates:
Do you have anybody that has used it for dementia and Alzheimer’s?
Rowena Gates:
We do, yes, absolutely!
Donna Gates:
And what kind of results have they gotten. I guess it depends on how severely, do you have mild, very mild, beginning stages, I think that is where it would obviously be the most beneficial and then if you are way down the road and you are gone, you probably cannot bring it back.
Rowena Gates:
We have had people at all different levels, and they definitely find it helpful. It is hard to discuss it without it being sort of a medical claim, but if you just think of their mental well-being and mental function, it does not matter if the brain is damaged or not, it is a noticeable improvement in those areas and there are illnesses like Alzheimer’s that is very directly related to misfolded proteins. So, if you can improve your protein function, that is just a really good thing.
Donna Gates:
And athletes, people that are physically injured, did they recover faster, I would think so?
Rowena Gates:
Yes, absolutely. There is a whole string of them of professional, especially professional baseball pitchers, because their arm takes a lot of wear and tear. Actually, their whole body does, but they will use it for faster recovery, and we have had quite a few of them, and it is really a key part of how they stay healthy, because there is such a stress on the body.
Donna Gates:
Well, when you were talking, I kind of jotted out some notes. I was going to say the three things that I can see that it does, it accelerates the repair of damaged proteins, there are fewer DNA breaks, and if someone is using the NanoVi, then they are having fewer DNA breaks, so that is definitely got to be antiaging. If you are not having these breaks in your DNA, that is to me probably number one there, but it also improves protein activity. I know that is what I heard you say, but could you just explain that a little bit more. I did not hear you say those exact words. So, if you do not mind, just kind of elaborating on that.
Rowena Gates:
That is kind of the core of what we are doing, improving the protein activity, protein function. We do that by creating a better watery environment that helps the proteins to do their job more readily – to fold and then function. That is a really key aspect of every aspect of health, because proteins do all the work in the body, including going back to repair the DNA damage, so damage to the primary DNA is one aspect of it, there is still all these other areas that are exposed. The DNA is less exposed to oxidative stress than maybe anywhere else in the body. It is kind of sequestered away so that it is protected more, but throughout the rest of the process of moving it into the RNA and ribosomes and the proteins and so on, there is all this exposure. Those are areas where you can reduce the oxidative stress and you do that by having it fixed right away, (what our device is helping to do), and all the repair is done by proteins.
Donna Gates:
Yeah, I just had a flashback actually, now I remember how I found you. I had a friend that had a NanoVi, and he went out of town for a couple weeks and he said I am just going to leave my NanoVi with you. I want you to try it out, and that is when I first got exposed to it, but what really, really impressed me was he had to have an operation. I forget what was wrong, but where they had to open his chest, because this is a long time ago. But he healed so fast, I was shocked, and that was it for me, that is when I started trying to ask you “how is this working?”. I do not understand it, and of course now, you have done a great job explaining it, but you did not tell me that back then, because I just did not even understand it all yet. But I am very grateful that I learned about it from Kim. So, is there anything else that you want to say about the NanoVi device or anything that pops into your mind before we close?
Rowena Gates:
Well, just really quickly we talked about the mental and physical performance and there is repairing for diseases, there is also this ‘just healthy aging’ aspect of it. I want to just mention that because, thanks to people like you, there is more and more interest in that area. As people recognize, “oh, no I need to prevent the illnesses, not try to recover later,” and I have to say it has been one of the most fun things about our company is to see that transition in the thinking of people. There are so many healthy people that get the device now for prevention, whereas it used to be, Donna the first 10 years I knew you probably, it was almost all related to recovering from chronic illness, because that you need repair and regeneration to recover from chronic illness. And now it is just so fun to see so many healthy people who are really enthusiastic about maintaining or even improving, be even better more high performance than, “oh my gosh, I have got to do a diving catch and save my health at the last minute.”
Donna Gates:
I am glad you said that, because I went to bed last night thinking about something very similar. I have been doing this for a really long time, and people were not interested at all; very, very few people were. They were still thinking sugar was good for you, and that is the only way you got energy. But we have come a long way, and now this younger generation, I would say 40s and even the younger generations down to the millennials, they are truly interested in their health. And they are starting to do the things to prevent aging now, which is great, because that is the time you want to start, actually you want to start preventing aging in the womb, but the 30s, 40s, that is great too. You know when I was little, not so little, I was like seven, I remember we were at a family reunion, and one of my aunts rolled my great-grandmother in, just my great-aunt like actually, she rolled in my great grandmother, so that was her mother, and I remember looking at her, and she had really pure white hair and you can see through it. She had tons of spots all over her body. She was very flabby, no muscle tone, and she was in a wheelchair. So, I looked at her and I thought, you know, does God really do this to us. We have to be young and having a good time in life and I was about seven, running around the summer in the road, grass, and everything and having a great time. Then I look at her and I think, “gosh you know are we going too, that is it, that is our destiny,” like that is what we have to go through to get out of here. And it was at that moment that I decided if there is another way that is possible, I am going to find it. I actually have been interested in anti-aging my whole life. So, I am really quite interested, and I am really happy to see the younger people. And of course, I am always thrilled when I can find a device like the NanoVi, because you know I am 73, and I do not suffer from a whole bunch of things that a lot of people in their 70th decade of life suffer from. Having this out there, and it is persisting, because you honestly – to tell you the truth, I thought I do not know if people are going to understand this and what a really good thing it is. But now with this extra science behind it, hopefully in our talk there will be more people understanding.
Rowena Gates:
Well, thank you. It is such a pleasure to be here.
Donna Gates:
Thank you very much. And how can people find the NanoVi, and is it okay for them to talk directly to you, to Rowena Gates?
Rowena Gates:
Absolutely, it would come in through the main line on our phone and our website is eng3corp.com, which is eng3corp.com, and so there is lots of information there or you can call anytime, and I am delighted to speak with people.
Donna Gates:
Great. Rowena, thank you very much.
Rowena Gates:
Thank you so much Donna, it is a pleasure.
